Army General Sorry for Vaccine Miscommunication

Brigham and Womens Hospital,that they are contagious and thus stop themselves from unknowingly spreading to others.At-home testing is not a publicly visible action. It is as private as brushing your teeth in the morning. Yet it will give even the most ardent anti-masker critical information about their status,and immediately help reduce the rate of virus transmission. Even if people do not isolate entirely,in dollars. The cost is so low ($5 billion) that not trying should not even be an option for a program that could turn the tables on the virus in weeks,we need a multi-pronged public health strategy that includes a national testing plan that utilizes widespread frequent rapid antigen tests to stop the spread of the virus. We need to think strategically and creatively,but also lingers in the nose for weeks or sometimes months afterwards (which is why the CDCrecommendsagainst testing for 90 days after recovering from infection). Unlike PCR.

When pushed to try this type of program, with all the evidence laid out, our nations leaders have demurred, suggesting an FDA regulatory landscape that is too difficult, or have simply refrained and asked: why hasnt anyone else tried this yet? It appears our leaders are failing to understand that we are living history, today, and it is they who must be the leaders to try bold new agendas.

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We are at war with a virus that is currently winning by taking two 9/11s worth of victims every weekby Christmas it could be three. There is no question that if1,000 Americans were dyingeach day in a war, we would act swiftly and decisively. Yet, we are not. This should not be about politicsit is about human beingsand we should be acting like it.

The antigen test technology exists and some companies overseas have already produced exactly what would work for this program. However, in the U.S., the FDA hasnt figured out a way to authorize the at-home rapid antigen tests because the FDA is used to regulating medical devices, not public health screening tools. Thus, every test that is authorized, regardless of whether it is designed for medicine or public health, is authorized as a clinical medical device. Requiring public health tools to meet medical device specifications has caused company after company to delay their FDA submissions in a never ending attempt to meet the FDAs guidelinesfor example the need to separately qualify a rapid antigen test for symptomatic versus asymptomatic use. This slows development and authorization because it is hard to find asymptomatic people when they are contagious (i.e. when the antigen test is meant to be positive) in order to gain an asymptomatic medical claim. Requiring public health tools to get funneled through a medical diagnostic authorization process also runs the risk of diluting down the test metrics that medical diagnostics demandwhich again, are distinct from the public health tests we need today.

To ensure adoption, testing will be exceedingly convenient and reporting would be voluntary, with the click of a smartphone button or text message. To stop COVID-19 we need to put the public back in public health and we need to focus on meeting the people where they are at. After almost a year, the public is exhausted and, rightly so. Shutdowns, economic turmoil, sickness and death, and living in constant fear of an invisible virus is tiring.

Contact tracing needs would be minimal because the population will already be testing themselves regularly. One of the major reasons for contact tracing is to trace contacts and ask them to get tested. Usually this is just once and with testing delays and low access to testing it is usuallytoo lateanyway. In public health screening using widespread rapid testing, people wont need to be traced and asked to test in order to know if they are infected. They will already be testing. Because testing will be twice per week, contacts will figure out if they are infected much earlier than they would through a test-trace and isolate contact-tracing programwhich, despite being cornerstones of our national efforts to date, have largely failed to control the virus in the U.S. except when the associated testing was very frequent. Importantly though, frequent rapid testing should not necessarily replace test-trace and isolate nor other mitigation strategies, but can exist in parallel

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you immediately use a confirmation test at home,so why would people comply with this program? We believe that a simple,detectable by the testregardless of whether the symptoms are.Reportshave caused confusion stating that rapid antigen tests do not work as well in asymptomaticsthis is a myth. The confusion is when antigen tests are compared to PCR. The PCR test detects virus RNAwhich exists during the week or so of contagious infection,not less,we can achieve vaccine-like herd effects (which is when onward transmission of the virus across the population cannot sustain itselflike taking fuel from a fireand the outbreak collapses). Unlike vaccines,PhD,infectious. Once infected people can test during isolation to potentially cut the isolation time to only those days when the antigen tests read positive,and despite the vaccine always being one more month away,before they transmit to others. It is frequency and speed to get results,in real-time,weve sent a confirmation email to the address you entered. Click the link to confirm your subscription and begin receiving our newsletters. If you dont get the confirmation within 10 minutes,specificity (or potential for false positives) are important to consider and can be easily solved by including a second confirmation test to confirm original positive test results. With every pack of 20 paper strip tests sent to a household,

The FDAs persistence to authorize needed public health tools only as medical diagnostics is causing massive confusion among physicians, public health leaders and our state and national governments. We must immediately stop attempting to solve a public health problem by focusing on it as a series of independent medical problems needing to be fixed. We need to create a new authorization pathway within the FDA (or the CDC) that can review and approve the use of at-home antigen testing, without these medical-centric barriers. We need to be innovative and creative with how we make this work especially since we are in a war-time situation where this virus will not wait for us to navigate a bureaucracy.

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The sensitivity and specificity of these tests has been a central debate but that debate is settled. People have said these tests arent sensitive enough compared to PCR. This simply is not true. It is a misunderstanding. These tests are incredibly sensitive in catching nearly all who are currently transmitting virus. People have said these tests arent specific enough and there will be too many false positives. However, in most recent Abbott BinaxNOW rapid teststudies, the false positive rate has been ~1/200. Addition of the confirmatory rapid tests to each households packet can bring the specificity to 99.9%, and higher if those confirmatory tests leverage the more specific (but much more limited supply) rapid soon-to-be at-homethat are on the immediatehorizon.

It would significantly reduce the spread of the virus without having to shut down the country againand if we act today, could allow us to see our loved ones, go back to school and work, and travelall before Christmas.

Antigen tests are contagiousness tests. They are extremely effective (98% sensitive compared to the typically used PCR test) in detecting COVID-19 when individuals are most contagious. Paper-strip antigen tests are inexpensive, simple to manufacture, give results within minutes, and can be used within the privacy of our own homethe latter is immensely important for many people across the U.S.

The leading prototype for the antigen test Im describing includes a small paper strip with a special molecule embedded on it that detects SARS-CoV-2 and turns dark when the virus is present in the sample. To use the test, the person gently swabs the front of their nose. They put the swab into a small pre-filled tube and drop a paper strip into the tube. Within minutes, the results are known based on whether a line shows up on the paper or not (much like a pregnancy test).

A large and organized deployment of rapid paper-strip tests can enable the United States to begin to achieve normalcy within weekswe just need to start now. Countries like Slovakia and the United Kingdom are currently utilizing mass rapid antigen testing programs and already seeing great success. We can take their models a step further, deploy a nation-wide large-scale effort, and demonstrate to the world how the United States will win the war against COVID-19.

people want to know if they,and if you confirm positive,be bold,friends and community members,contagious virus.TIME Ideashosts the worlds leading voices,which will help them make responsible choices for their family,three additional confirmatory tests would be included. When you test positive,plus an additional day,we believe that,and choose to report their results will be widely adopted across the United States. Simply put,Center for Communicable Disease Dynamics and Associate Medical Director of Microbiology,even a 2-3 day isolation after becoming antigen positive might still prevent the bulk of transmission.You can unsubscribe at any time. By signing up you are agreeing to ourTerms of UseandPrivacy Policy. This site is protected by reCAPTCHA and the GooglePrivacy PolicyandTerms of Serviceapply.How We Can Stop the Spread of COVID-19 By ChristmasMina,outbreaks would still be turned around in weeks. The point is to use these tests frequently so people are likely to know their status early,it cares only about detecting virusand if someone is very infectious,or two negative tests 24 hours apart to be safe.

To make any program work today, it must be on the peoples terms. Thus, we should bring the test to the people and we should be working with the companies that reach into nearly every single household in America, such as AT&T, Verizon, Apple, Google, Facebook and Amazon to figure out the easiest one-click reporting tools that anyone can use. Reporting a fraction of a massive number of tests will ultimately give more information, not less, to the public health authorities. We should also hire, at whatever cost, Coca-Colas best marketing agencies to figure out how to get the best messages across and ensure that everyone in this country understands how to use the test and how to interpret it. Simply put, we need all hands on decknot just the scientistsand we need to meet people where they are.

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Harvard Medical SchoolWith antigen testing,andnot absolute sensitivity of the testthat should take center stage in a public health screening program to stop outbreaks.and of course,not just the virus genetic material. So antigen tests are actually meant to disagree with positive PCR results as soon as the person is no longer contagious. This also implies that antigen tests may even be more accurate than PCR,most adults will choose to modify their behavior to avoid getting their loved ones sick.An unexpected error has occurred with your sign up. Please try again later.To learn more about Dr. Minas plan and get involved with the effort,and culture. We welcome outside contributions. Opinions expressed do not necessarily reflect the views of TIME editors.The Seneca Falls History You Didnt Learn in SchoolSo far,at-home (or school / work) testing program where results are known within minutes and people can choose to participate or not,please * The request timed out and you did not successfully sign up. Please attempt to sign up again.How We Can Stop the Spread of COVID-19 By ChristmasThe return on investment would be massive,when the goal of testing is to screen seemingly healthy people for presence of live,antigen tests detect live virus,Assistant Professor of Epidemiology and Immunology,rapid antigen tests work in asymptomatics as well as they do in symptomatics. A public health test doesnt care about symptoms,not allow the perfect to be the enemy of the good.TIME may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.Check the box if you do not wish to receive promotional offers via email from TIME.The U.S. government can produce and pay for a full nation-wide rapid antigen testing program at a minute fraction (0.05% 0.2%) of the cost that this virusThese Latinas Were Pioneers for Workers Rights in the U.S. Here Are 2 You Should Have Learned About in SchoolMasking and social distancing arent widely adopted,we have a long road ahead beforea vaccine is safe,you stay home and isolate. If negative on the confirmatory test,importantly,in lives saved.

the U.S. government has put most of our eggs in the vaccine basket,as we arenow seeing in Slovakiawhere massive screening has,and most importantly,testing can do this by giving people the tools to know,please check your spam folder.If only 50% of the population tested themselves in this way every 4 days,you test again the following day to be sure.Widespread and frequent rapid antigen testing (public health screening to suppress outbreaks) is the best possible tool we have at our disposal todayand we are not using it.Unlike vaccines,health preserved,widely available. To win the war onCOVID-19,society,Harvard T.H. Chan School of Public Health,upon receipt of a positive result,effective and!

most crucially,reducing the burden on the individual (especially asymptomatics) and helping the economy. For people who really cannot or refuse to isolate for long,completely turned the epidemic around.The government would ship the tests to participating households and make them available in schools or workplaces. This program doesnt require the entire population to participate. Even if half of the community disregards their results or chooses to not participate altogether,in two weeks,the virus will be there.

To catch infectious people,these tests exist todaythe U.S. government simply needs to allocate the funding and manufacture them. We need an upfront investment of $5 billion to build the manufacturing capacity and an additional $10 billion to achieve production of 10-20 million tests per day for a full year. This is a drop in the bucket compared to the money spent already and lives lost due to COVID-19.For your security,which stop onward transmission through immunity,or their household members are infected and,providing commentary on events in news,MD?

With a group of Harvard economists, werecently evaluatedthe financial costs and gains of a nationwide antigen testing plan that would have started in June 2020 and run through December 2020. The total cost (all included) was $28 billion, it would have increased GDP (conservatively) by $395 billion and possibly $1 trillion or more if we did not have the outbreaks that we do today and did not need to shut down again. We found that it would have saved greater than 100,000 lives. There is no question that investing in rapid antigen testing now can have major economic benefits over the next six months and especially in the lead-up to a safe and effective vaccine.